A cytotoxic haemolysin from Treponema hyodysenteriae--a probable virulence determinant in swine dysentery

Serotype-specific protection against Treponema hyodysenteriae infection in ligated colonic loops of pigs recovered from swine dysentery.

Resistance to Treponema hyodysenteriae (serotypes 1, 2, 3, and 4) infection was evaluated in ligated colonic loops in pigs recovered from swine dysentery. Lesions were present in most loops from recovered swine inoculated with heterologous serotypes; however, lesions were not present in loops of recovered swine inoculated with homologous serotypes.

Bactericidal effect of normal swine sera on Treponema hyodysenteriae.

Treponema hyodysenteriae was incubated in 20% normal swine sera (NSS) at 37 degrees C for 4 h, and viability was determined by a plate dilution method. NSS was bactericidal for nonpathogenic T. innocens and avirulent T. hyodysenteriae, but not for virulent T. hyodysenteriae isolates. Heat inactivation at 56 degrees C for 30 min, treatment with EDTA or EGTA [ethylene glycol-bis(beta-aminoethyl e...

Isolation of Treponema hyodysenteriae from wild rodents.

Rodents from swine-producing farms were examined for the presence of Treponema hyodysenteriae. Wild mice (n = 257) and rats (n = 41) were trapped on eight farms. Ceca were removed aseptically, and the contents and mucosal scrapings were cultured on selective medium (blood agar containing 400 micrograms of spectinomycin per ml). T. hyodysenteriae was detected in the cecal scrapings of four mice ...

Environmental Contamination is a Major Contributor to Prevalence of Serpulina hyodysenteriae Infection of Swine on Farms Medicating Against Swine Dysentery

A nonessential African swine fever virus gene UK is a significant virulence determinant in domestic swine.

Sequence analysis of the right variable genomic region of the pathogenic African swine fever virus (ASFV) isolate E70 revealed a novel gene, UK, that is immediately upstream from the previously described ASFV virulence-associated gene NL-S (L. Zsak, Z. Lu, G. F. Kutish, J. G. Neilan, and D. L. Rock, J. Virol. 70:8865-8871, 1996). UK, transcriptionally oriented toward the right end of the genome...